The 49-year-old Meacham has been a valuable contributor in coaching and recruiting in the Cowboys program after coming to Stillwater following coaching stints including offensive coordinator duties at Samford (2002-04), Henderson State (1999-2002), Jacksonville State (1997-99) and Georgia Military (1991-96).
With Houston, Meacham inherits an offense off a 5-7 team that started 0-3 with losses to bowl teams Louisiana Tech (56-49) and UCLA (37-6).
The Cougars, who fired their offensive coordinator after an opening loss to Texas State, averaged 32.4 points and 480.8 yards (151.2 rushing and 329.7 passing) a game.
Houston returns two of their most important offensive contributors in running back Charles Sims, who rushed for 851 yards and 11 touchdowns this season, and quarterback David Piland, who completed 57 percent of his passes for 2,944 yards with 16 touchdown passes and 12 interceptions.
At Oklahoma State, Meacham helped a Cowboys offense that averaged at least 40 points and ranked among the nation's top 10 in total offense in five of the last six seasons. He served as passing game coordinator in 2008-09.
Meacham's departure may make the open offensive coordinator job at Oklahoma State that much more attractive as Gundy could allow the potential new offensive coordinator to have a heavy influence in who is hired to replace Meacham on the offensive staff.
In other words, the new coordinator may get to bring in a coach of their choosing on the staff. That was a luxury not afforded to either of the past two offensive coordinators in Todd Monken or previously Dana Holgorsen.